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Chemotherapy
Experts agree that for most breast cancer cases, chemotherapy
is not the first treatment of choice. But for those for whom it
is appropriate, it can provide effective, long term
results.
Chemotherapy consists of using drugs to combat cancer. With the
increasing sophistication of pharmacology, those drugs are
safer, more effective and more targeted, with fewer side
effects than ones of the past. Today, it's common to use a drug
'cocktail' in order to offset side effects and provide a more
effective treatment.
The drugs used typically interfere with the cells' ability to
divide, since that is one of the chief characteristics of
cancers, an uncontrolled growth from abnormal cell division in
breast cancer tissue.
Chemotherapy is often chosen when the cancer has become more
advanced, requiring more a rigorous response to eradicate
cancer cells. Cancer cells clumps can grow and metastasize
(spread of a primary tumor to other areas, forming secondary
tumors of similar type). That condition may indicate that
chemotherapy is an appropriate regimen.
Cancers can recur. The causes are still poorly understood. In
some cases it may be that the initial cancer wasn't entirely
eradicated. Or, it may be that the underlying cause that
generated the tumor is still present and active, causing the
cancer to regenerate. But whatever the basic reason,
chemotherapy is often used in such cases.
But one of the more serious complications with chemotherapy
treatments is related to its side effects. Though the drugs are
improving in this regard, chemotherapy treatments sometimes
affect healthy cells as well as cancerous ones. That results in
healthy systems being harmed and lessened in function.
Since some of that function is to fight disease such as the
cancer itself, a double harm occurs. Radiation therapy has a
similar drawback in that it compromises the immune system,
which is part of what helps to fight the cancer and its
effects.
The digestive system is often affected in negative ways,
leading to nausea, common among those undergoing chemotherapy
treatments. Hair loss is a by-now familiar effect. But
chemotherapy can even affect the composition of bone marrow,
which leads to a number of harmful effects. Bone marrow
performs several functions in the body. Foremost among them is
aiding in the production of red and white blood cells.
Damage to heart, kidney and other organs is possible, though
this is uncommon since cells in these organs don't divide as
frequently under natural circumstances. In some studies, memory
and concentration loss were associated with chemotherapy
treatments. Older female patients often find the reproductive
cycle altered, bringing on premature menopause. 'Female
patients' is specified here since men, too, can contract breast
cancer.
Still, drugs in use today are better tolerated and more
targeted that those of previous generations. They may help cut
off vessels that supply blood to the tumors which encourage the
growth of just such vessels to feed themselves. There are a
variety of chemotherapy regimens, with each one designed for
the individual patient and his or her circumstances.
Though never pleasant, chemotherapy provides an important tool
in the fight against what was once an almost always fatal
disease. Today, long term survivability is greater than ever
with fewer long-term side effects. Chemotherapy is one of the
reasons.
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